but one sibling is in South Africa
This family, from the mother with the syndrome, is composed of 3 siblings (two female, 1 male), each of whom is affected. Each sibling has had children (Female A: 1 girl and 1 boy; Female B: 1 girl [unaffected] and 1 boy; Male: 2 girls). Therefore, out of 3 children and 6 grandchildren, only 1 is unaffected.
Ages as of writing are: Mother: deceased; Female A: 48; Female B: 44: Male: 39. The grandchildren are aged between 13 and 2.